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  • Title: [Pre-operative chemotherapy of stomach cancer combined with local administration of OK-432--evaluation of macroscopic results].
    Author: Mukai M, Den N, Yamazaki Y, Namiki S, Oda S, Nagao K.
    Journal: Gan To Kagaku Ryoho; 1982 Jan; 9(1):96-102. PubMed ID: 6820880.
    Abstract:
    We have developed OMF treatment which is consisting of endoscopical injection of OK-432 into the perilesional area of cancer, intraarterial or intravenous injection of mitomycin C by one shot and oral administration of 5-FU, and applied it to the patients with preoperative gastric cancer to whom remarkable macroscopic effects were obtained. We determined its efficacy by establishing a response criteria. Although there were no excellent results, the clinical results were rated as good in 5 lesions (50%) and as fair in 5 lesions (50%) out of 10 lesions in 9 cases. In none of the cases, the treatment was ineffective.
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