These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Lymphocyte receptors for human erythrocytes in newborn infants and adults. Expression on fresh and lectin-stimulated cells.
    Author: Hallberg A, Hallberg T.
    Journal: Int Arch Allergy Appl Immunol; 1983; 70(2):100-7. PubMed ID: 6822437.
    Abstract:
    Lymphocyte receptors for human erythrocytes (HRBC) have been demonstrated by an optimized technique using neuraminidase-treated HRBC and high-protein diluent. Mean values of 55 and 50% reactive lymphocytes were found in the peripheral blood of newborn infants and adult donors, respectively. The HRBC receptor was labile under tissue culture conditions in vitro, in contrast to the receptors for sheep erythrocytes, Fc of IgG, and complement. Short-term culturing of lymphocytes with T cell mitogens (phytohemagglutinin, concanavalin A) increased the proportion of HRBC-receptor-bearing lymphocytes. Pokeweed mitogen, being mainly a B cell stimulator, was less effective in activating lymphocytes to resynthesize the receptor. It is concluded that the HRBC receptor is probably not a stable marker for a single subpopulation of human T lymphocytes. During the first week of life, the HRBC receptor is expressed on at least the same proportion of peripheral blood lymphocytes as in adults.
    [Abstract] [Full Text] [Related] [New Search]