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  • Title: [Immunologic disorders and their significance in the treatment of cervical cancer].
    Author: Grinevich IuA, Dziubko NIa, Kokhanevich EV, Vinnitskaia VB, Klevetenko MP.
    Journal: Vopr Onkol; 1983; 29(1):43-8. PubMed ID: 6823754.
    Abstract:
    The study is concerned with immunologic status (cell-mediated and humoral immunity) as a factor influencing the choice of scheme of treatment for carcinoma of cervix uteri. The indexes of immunocompetence should be taken into account in planning the differential treatment of precancer and early forms of carcinoma of cervix uteri. Radiation treatment exerts an immunosuppressive effect. However, immunologic indexes are not affected considerably by laser destruction or surgery. Cryodestruction has a beneficial effect on cell-mediated immunity. Considering these effects as well as the long-term results of different procedures of treatment, laser coagulation, cryogenic destruction or diathermoconization should be recommended for management of carcinoma in situ of cervix uteri, and extensive extirpation of the uterus, unattended by radiation, for Tla.
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