These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Estimating eighth nerve survival by electrical stimulation.
    Author: Smith L, Simmons FB.
    Journal: Ann Otol Rhinol Laryngol; 1983; 92(1 Pt 1):19-23. PubMed ID: 6824273.
    Abstract:
    Determining nerve survival is important in selecting patients for cochlear implants, and in predicting outcomes from such implants. In search of a possible method we deliberately destroyed nerve fibers (ganglion cells) in 17 cat cochleas to produce a range of degenerations. Months later, we electrically stimulated these ears (and seven controls) and recorded electrical ABR input-output functions. Cats with no surviving ganglion cells showed no ABR activity. Cats with 5%-10% surviving cells had ABRs which typically had normal thresholds but decreased input-output functions. The suprathreshold slopes of these input-output functions reliably predicted ganglion cell survival for all degrees of degeneration. Thus, perceptual (or electrical) threshold is a poor indicator of nerve survival. Loudness growth (or growth in the electrically-induced auditory brainstem response) is a good index of surviving ganglion cells.
    [Abstract] [Full Text] [Related] [New Search]