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  • Title: Tracheobronchial clearance after flexible fiberoptic bronchoscopy.
    Author: Lundgren R, Grubbström J, Philipson K, Haglund S, Mossberg B, Camner P.
    Journal: Eur J Respir Dis; 1983 Jan; 64(1):3-8. PubMed ID: 6825746.
    Abstract:
    As the tracheobronchial mucosa is vulnerable to mechanical trauma it is important to investigate whether examination with a flexible fiberoptic bronchoscope (FFB) damages the respiratory mucosa. In 12 subjects, tracheobronchial clearance was measured 1 day before and 1 day after FFB performed under topical anaesthesia. Mucociliary transport was studied by having the patients inhale 6 micron teflon particles tagged with 99mTc, and by external measurements of the radioactivity retained in the lungs. Most of the patients had a similar clearance on both days. A marked impairment after FFB was only seen in one patient. This study suggests that the tracheobronchial clearance system has a large reserve against mechanical trauma. FFB may possibly change mucociliary clearance in some patients, and this can be of practical significance in patients unable to cough.
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