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  • Title: Detection of hematoporphyrin fluorescence during fiberoptic bronchoscopy to localize early bronchogenic carcinoma.
    Author: Kinsey JH, Cortese DA, Sanderson DR.
    Journal: Mayo Clin Proc; 1978 Sep; 53(9):594-600. PubMed ID: 682688.
    Abstract:
    Photoelectric detection of fluorescence from hematoporphyrin-containing "occult" bronchogenic carcinoma is a potentially useful technique for localizing and delineating such cancers. A method is presented which would enable use of a fluorescence-detection system simultaneously with conventional illumination during flexible bronchofiberscopic examination. Preliminary data suggest that quantities of hematoporphyrin as small as 5 picograms can be detected on the surface of tumors by this method.
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