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  • Title: The use of glucagon in hydrostatic reduction of intussusception: a double-blind study of 30 patients.
    Author: Franken EA, Smith WL, Chernish SM, Campbell JB, Fletcher BD, Goldman HS.
    Journal: Radiology; 1983 Mar; 146(3):687-9. PubMed ID: 6828682.
    Abstract:
    Thirty patients were referred for hydrostatic reduction of ileocolic intussusception. Children with suspected gangrenous bowel or sensitivity to glucagon were excluded from the investigation. A standard protocol for the procedure was used in all patients, including the intravenous administration of glucagon or placebo (0.05 mg/kg) when the intussusception was encountered. Successful reduction was achieved in 53% of both control and glucagon-treated patients. Analysis of the length of the procedure and the ease of reduction of the intussusception indicated no difference in the two groups. This multicenter double-blind study failed to show any therapeutic value of glucagon in hydrostatic reduction of intussusception.
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