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  • Title: [Influence of erythrocyte destruction kinetics on the dynamic behavior of the erythropoiesis system].
    Author: Flerov MN, Dibrov BF.
    Journal: Biofizika; 1983; 28(1):103-7. PubMed ID: 6830880.
    Abstract:
    A simple mathematical model was used to analyse the influence of cell destruction kinetics on the dynamics of erythropoietic system. Two ways of erythrocyte destruction were compared: random destruction and destruction of cells at their maximum age. It has been shown that mostly used description of erythrocyte destruction as a random process results in a great stability increase (about three times in the critical feedback coefficient). Oscillations with large periods (20 divided by 200 days) may exist in the system.
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