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  • Title: Trimethoprim-sulphamethoxazole and thrombocytopenia.
    Author: Dickson HG.
    Journal: Med J Aust; 1978 Jul 01; 2(1):5-7. PubMed ID: 683114.
    Abstract:
    Thrombocytopenia is an uncommon but serious side effect of the antimicrobial combination of trimethoprim and sulphamethoxazole. Thirty-one cases in seven years, including two deaths, have been reported to the Australian Adverse Drug Reactions Registry. Females were affected twice as frequently as males. In 70% of the patients platelet counts were 20x10(9)/L or less. Thrombocytopenia which is associated with this agent may occur at any age.
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