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  • Title: Monoamine oxidase inhibitors in obsessive-compulsive disorder.
    Author: Jenike MA, Surman OS, Cassem NH, Zusky P, Anderson WH.
    Journal: J Clin Psychiatry; 1983 Apr; 44(4):131-2. PubMed ID: 6833198.
    Abstract:
    The authors describe the use of monoamine oxidase inhibitors (MAOIs) in eight patients with severe obsessive-compulsive disorder. In four cases, the MAOIs produced rapid and sustained remission of symptoms; no response was seen in four other patients. All patients who responded to MAOIs, but none of the nonresponders, had phobic anxiety and/or panic attacks. Thus, a trial of MAOIs is indicated in obsessive-compulsive disorder, especially when phobic anxiety or panic attacks form part of the clinical picture.
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