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  • Title: [Morphogenesis of transverse straited muscles].
    Author: Ontell M, Klueber K.
    Journal: Ontogenez; 1983; 14(1):3-20. PubMed ID: 6835645.
    Abstract:
    During the past 50 years there have been significant advances in our understanding of striated muscle development, both from tissue culture studies and from observations of myogenesis in the developing foetus. Experiments, using the distinctive nucleolar marker of quail nuclei, have led to reexamination of the source of the body's muscle masses. Advances have been made in our understanding of the events which occur and mechanisms involved in the formation of multinucleated myofibers from mononucleated myoblasts. Recently, the development of entire muscle organs has been studied. The present review attempts to synthesize the results of both in vivo and in vitro studies of myogenesis, comparing both their similarities and their differences. Attention has been focused on recent advances in our understanding of the source of muscles in the intact foetus, the formation of extrafusal and intrafusal fibers, and the development of the afferent and efferent neuromuscular relationships.
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