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Title: Hyposplenism in primary systemic amyloidosis. Author: Gertz MA, Kyle RA, Greipp PR. Journal: Ann Intern Med; 1983 Apr; 98(4):475-7. PubMed ID: 6838069. Abstract: Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p less than 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.[Abstract] [Full Text] [Related] [New Search]