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  • Title: The inhibitory effect of some lectins on the differentiation of Friend erythroleukemia cells.
    Author: Bosman GJ, Boer P, Steyn-Parvé EP.
    Journal: Biochem Biophys Res Commun; 1983 Jan 14; 110(1):228-34. PubMed ID: 6838513.
    Abstract:
    Growth and differentiation of Friend cells can be inhibited by treatment with concanavalin A and wheat-germ agglutinin. This inhibition is specific for cells that are in the early stages of the differentiation process (24-48 h after the addition of dimethyl sulfoxide) and is reversible upon treatment with the sugars competitive for these lectins. These results suggest a regulatory role for some plasma membrane-bound glycoproteins early in the differentiation of Friend erythroleukemia cells induced by dimethyl sulfoxide.
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