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  • Title: On the mechanism by which Mg2+ and adenine nucleotides restore membrane potential in rat liver mitochondria deenergized by Ca2+ and phosphate.
    Author: Toninello A, Siliprandi D, Siliprandi N.
    Journal: Biochem Biophys Res Commun; 1983 Mar 29; 111(3):792-7. PubMed ID: 6838586.
    Abstract:
    The presence of ATP or ADP in the incubation medium prevents the collapse of membrane potential induced by external Ca2+ and phosphate. The same adenine nucleotides are unable to restore collapsed membrane potential unless Mg2+ are also added. Bongkrekate is also able to prevent the effects of external Ca2+ and phosphate and when added after membrane potential has collapsed strongly potentiates the restorative action of ATP or ADP. Atractyloside has an opposite effect.
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