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  • Title: Radial maze performance in three strains of mice: role of the fimbria/fornix.
    Author: Reinstein DK, DeBoissiere T, Robinson N, Wurtman RJ.
    Journal: Brain Res; 1983 Mar 14; 263(1):172-6. PubMed ID: 6839169.
    Abstract:
    Three strains of mice were tested on an 8-arm radial maze, an index of hippocampus-dependent spatial memory. Levels of performance differed between strains with C57Br/cj greater than Balb/cj greater than C57Bl/6j. Lesions of the fimbria/fornix disrupted performance in the C57Br and Balb strains: the C57Bl mice never performed better than chance before or after surgery. Choline acetyltransferase activity in hippocampus was not correlated with radial maze performance. These findings suggest a possible genetic contribution towards radial maze behavior.
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