These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Determination of aspartate aminotransferase isoenzymes in hepatic diseases--preliminary findings.
    Author: Panteghini M, Falsetti F, Chiari E, Malchiodi A.
    Journal: Clin Chim Acta; 1983 Feb 28; 128(1):133-40. PubMed ID: 6839500.
    Abstract:
    The study sought to establish a relationship between the AST isoenzyme levels in serum and degree of hepatic damage, by using a new and simple immunochemical method for the differential determination of the isoenzymes. Sixty-nine patients with various hepatic diseases were studied. During hepatic damage, cytoplasmic isoenzyme (s-AST) is found in greater quantities than mitochondrial isoenzyme (m-AST), but the m-AST level increases to a greater extent in acute liver diseases. However, m-AST in alcoholic hepatitis is higher than expected from the total AST (t-AST) values. The ratio of m-AST to t-AST seems to discriminate alcoholic hepatitis from other liver diseases.
    [Abstract] [Full Text] [Related] [New Search]