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  • Title: Combined treatment of autochthonous 3-methylcholanthrene-induced murine tumors by immunotherapy and radiotherapy.
    Author: Ichinose Y, Yasumoto K, Tanaka K, Yaita H, Nomoto K.
    Journal: Gan; 1983 Feb; 74(1):143-7. PubMed ID: 6840433.
    Abstract:
    C57BL/6J mice with autochthonous 3-methylcholanthrene-induced tumors were given combined therapy with 2,000 rad of local irradiation and regional injections of cell-wall skeleton of Nocardia rubra (N-CWS). The greatest suppression of the tumor growth and the highest survival rate were observed in the combined treatment group as compared to the non-treated control, regional injections of N-CWS alone and irradiation alone groups. In addition, pulmonary metastasis was significantly suppressed by the combined therapy.
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