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  • Title: Comparative activity of amantadine and ribavirin against influenza virus in vitro: possible clinical relevance.
    Author: Browne MJ, Moss MY, Boyd MR.
    Journal: Antimicrob Agents Chemother; 1983 Mar; 23(3):503-5. PubMed ID: 6847176.
    Abstract:
    The activities of amantadine and ribavirin against influenza A viruses were compared against low-multiplicity (plaque inhibition) and high-multiplicity (protein synthesis inhibition) infections. Our results suggest that the predictive value of in vitro data for the clinic may be improved by consideration of tests against a high-multiplicity infection.
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