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  • Title: Clinical and laboratory evaluation of a commercial kit for measurement of serum free thyroxin ("Amerlex Free T4").
    Author: Nasralla M, Hassan M, Al-Ansari AA, Kutob M, Al-Abdul Razak A, Al-Awqati MA.
    Journal: Clin Chem; 1983 Jan; 29(1):164-6. PubMed ID: 6848256.
    Abstract:
    Different indexes of thyroid function were determined in conjunction with values obtained with a new commercial radioimmunoassay kit for serum free thyroxin, in 49 apparently healthy subjects, 87 pregnant women, and 142 outpatients attending the thyroid clinic. The results indicate a diagnostic success rate of 88% when free thyroxin was measured instead of estimating the so-called free thyroxin index. Furthermore, in three cases of papillary carcinoma the concentration of free thyroxin was increased, although all the other laboratory tests indicated a euthyroid state. Technically, the method is simple, rapid, and precise, and it would be of most value in the small hospital laboratory lacking the facilities of a comprehensive thyroid-function test service.
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