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  • Title: [Comparative study of the karyotype and histostructure of neoplasms of the uterine body, stomach and malignant melanoma].
    Author: Ganina KP, Polishchuk LZ, Gritsenko AF, Kireeva SS.
    Journal: Tsitol Genet; 1978; 12(3):257-62. PubMed ID: 684836.
    Abstract:
    Direct analysis of karyotype revealed a heterogeneity of chromosome composition, variations in modal lines and chromosome aberrations, diversity of marker chromosome morphology. The variability of cytogenetic alterations was found in tumors both of the same and of different origin. These results established the nature of genome and chromosome alterations in the investigated tumors. The problem is discussed of a possible use of cytogenetic analysis for a more concrete characterization of human tumors in terms of their biological features.
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