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  • Title: The dilemma of the creatine kinase cardiospecific iso-enzyme (CK-MB) in marathon runners.
    Author: Diamond TH, Smith R, Goldman AP, Myburgh DP, Bloch JM, Visser F.
    Journal: S Afr Med J; 1983 Jan 08; 63(2):37-41. PubMed ID: 6849159.
    Abstract:
    Serum creatine kinase iso-enzyme (CK-MB) levels were measured in 51 marathon runners before and after a 50 km marathon event. Ninety-five per cent of the runners were found to have pathologically elevated values, i.e. CK-MB concentrations were elevated to the range normally considered indicative of myocardial necrosis. Results indicate that a rise in the CK-MB level is common after marathon running. We therefore believe that cardiac enzymes are an unreliable indicator of myocardial infarction in patients who experience chest pain following strenuous muscular exercise.
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