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  • Title: [Effect of long-term immunization of rabbits of different ages with homologous heart antigen on blood lipid and lipoprotein content].
    Author: Zaĭchenko AP, Chaialo PP.
    Journal: Biull Eksp Biol Med; 1983 May; 95(5):57-9. PubMed ID: 6850091.
    Abstract:
    The data are provided on the content of lipid and lipoproteins in the blood of young and old rabbits during long-term immunization with homologous heart antigen (once a week for 2.5 months). Two weeks after the beginning of the experiment the blood of immunized animals showed cardiac antibodies whose content rose, especially in young animals, in the course of the experiment. The content of immune complexes circulating in the blood also increased, with this increase being more pronounced in old rabbits. During immunization, the blood levels of lipoproteins total cholesterol, and triacylglycerins in old animals increased earlier and more intensely.
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