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  • Title: Cyclacillin in the treatment of acute sinus infections and exacerbations of chronic infections.
    Author: Ordoñez FH.
    Journal: Clin Ther; 1983; 5(3):279-83. PubMed ID: 6850721.
    Abstract:
    Cyclacillin was used to treat 40 patients with bacterial sinus infections, either acute or exacerbations of chronic infections. The drug was administered orally in a dosage of 500 mg every six hours for ten days, although three patients required extended treatment. More than 70% of the patients had remission of symptoms in six days, and all but the aforementioned three had remission in ten days or less. More than 90% of the patients had a moderate to good response; only two patients had a poor response. The only side effects were gastrointestinal disorders, which disappeared with administration of antacids. No side effects were noted in 72.5% of patients. Cyclacillin proved to be an effective and well-tolerated antibiotic for infections of the paranasal cavities.
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