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  • Title: [Role of the suprachiasmatic nuclei of the anterior hypothalamus in regulating the circadian rhythms of rat locomotor activity].
    Author: Chaplygina SR, Nevretdinova ZG.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1983 Mar; 69(3):313-21. PubMed ID: 6852286.
    Abstract:
    Effect of bilateral lesions of suprachiasmatic nuclei (SCN) of anterior hypothalamus on circadian rhythms of locomotor activity in a treadmill was studied in blinded rats. Immediately after the SCN lesion the free-run circadian rhythm of locomotor activity disappeared: the animals became arrhythmic. Partial lesion of SCN weakened the circadian component of rhythm and led to irregular oscillations within 0.5--3.5 hrs range which put on circadian periodicity. Significance of the anterior hypothalamus SCN in organization of circadian rhythms in rats was discussed.
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