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Title: Buschke-Ollendorf syndrome. An electron microscopic study. Author: Reymond JL, Stoebner P, Beani JC, Amblard P. Journal: Dermatologica; 1983; 166(2):64-8. PubMed ID: 6852319. Abstract: Two identical twins with the Buschke-Ollendorf syndrome (dermatofibrosis lenticularis disseminata with osteopoikilosis) are described. Ultrastructurally elastic fibers show clumps of electron-lucent elastin material coated with fine fibrils. The fibroblasts show enlarged endoplasmic reticulum containing abnormal fibrillar material. Juvenile elastoma seems to be a better term than dermatofibrosis. The pathogenesis of the elastic defect is discussed.[Abstract] [Full Text] [Related] [New Search]