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  • Title: Cimetidine in gastro-oesophageal reflux.
    Author: Bennett JR, Buckton G, Martin HD.
    Journal: Digestion; 1983; 26(3):166-72. PubMed ID: 6852397.
    Abstract:
    15-hour intra-oesophageal pH monitoring and symptom scores were used to compare the effect of cimetidine, 1 or 2 g daily with placebo on patients with acid gastro-oesophageal reflux. Night pain and antacid consumption were reduced by cimetidine, but other symptoms did not show significant differences. Symptomatic improvement appeared greater in smokers than non-smokers. 15-hour intra-oesophageal pH measurements showed that the number of reflux episodes was reduced in the cimetidine-treated groups.
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