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  • Title: Immunoglobulins of rnu/rnu 'nude' rats with congenital aplasia of the thymus.
    Author: Taubman MA, Ebersole JL, Smith DJ.
    Journal: Immunology; 1983 Jun; 49(2):295-300. PubMed ID: 6852869.
    Abstract:
    The levels of immunoglobulins (Ig) in the serum and saliva of nude (rnu/rnu) congenitally athymic rats and control (rnu/+) thymic heterozygous rats have been studied. Serum IgM, and serum and salivary IgA levels were virtually identical between rnu/rnu and rnu/+ rats. Serum IgG was drastically reduced in nude rats during the period when endogenous IgG synthesis was predominant. The most consistent and pronounced differences in Ig levels between rnu/rnu and rnu/+ rats involved the IgG isotype.
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