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  • Title: [Features of the convulsive activity in the EEG of patients with classic phenylketonuria].
    Author: Lastochkina NA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1983; 83(3):79-86. PubMed ID: 6858502.
    Abstract:
    The problem of the genetic burden inherited by the human race represents one of the research priorities of modern medicine, with hereditary diseases of the nervous system, particularly oligophrenia, being a significant part of it. The author examined the EEGs of patients suffering from "classic" phenylketonuria, a hereditary defect of metabolism, and found a) constant presence of intensive convulsive activity in all regions; b) presence of involuntary motor activity; c) changes in the principal rhythms of the EEGs; d) monotonous pattern of responses in the form of delta-waves of a generalized nature or in the form of epileptiform activity of the "slow spike wave" type; e) presence of the most profound EEG changes in the frontal regions.
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