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  • Title: Association of centromeric heterochromatin with the nucleolus in mouse Sertoli cells.
    Author: Jean P, Hartung M, Mirre C, Stahl A.
    Journal: Anat Rec; 1983 Apr; 205(4):375-80. PubMed ID: 6859551.
    Abstract:
    In adult Sertoli cells of most strains of mice, all the centromeric heterochromatin is condensed in two chromocenters, one on each side of a single, large nucleolus. In a random-bred Swiss OF-1 strain, however, the nucleus has a different structural organization. Part of the heterochromatin Is seen as chromocenters in contact with the nucleolus; the rest of it is dispersed in granules of unequal size in the nucleoplasm. Such an unusual spatial arrangement of heterochromatin in interphase nucleus cannot be explained either by a difference in the nucleolar organizing regions or by a polymorphism of the C-banding of metaphase chromosomes.
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