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  • Title: Bone imaging in infections: artefacts from spectral overlap between a Tc-99m tracer and In-111 leukocytes.
    Author: Fernandez-Ulloa M, Hughes JA, Krugh KB, Chin D.
    Journal: J Nucl Med; 1983 Jul; 24(7):589-92. PubMed ID: 6864312.
    Abstract:
    In three patients with skeletal infectious disease, scintigrams with a Tc-99m bone-seeker and In-111-tagged leukocytes, made within 24 hr of each other, showed striking similarities. In two cases, the findings from the In-111 WBC images were ultimately determined to be artefacts due to Tc-99m crosstalk within the 173-keV photopeak of In-111. In the second case, the error was traced to failure to use a pure In-111 source for energy calibration: the camera had been peaked on the radiation from the patient himself, who had had an earlier Tc-99m bone scan.
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