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  • Title: [Elements predicting respiratory complications after total excision of neurinomas of the 8th nerve. Consequences on the postoperative treatment (study of 12 cases)].
    Author: Clergue F, Derenne JP, Tchotourian S, Sermet A, Pertuiset B.
    Journal: Neurochirurgie; 1983; 29(1):25-9. PubMed ID: 6866190.
    Abstract:
    Pulmonary complications are observed after radical surgery of acoustic neurinomas. This study, performed on 12 patients was undertaken to appreciate central respiratory activity by measuring the respiratory response to CO2 before and after the operation and to find out whether they could be used to predict post-operative respiratory complications. The patients who developped pulmonary or bronchial infections had increased PaCO2 (45.1 +/- 3.0 mmHg--mean +/- S.D.) and decreased ventilatory response to CO2 (VE/PACO2: 0.65 +/- 0.37 1/min/mmHg) before the operation. After the operation, all these patients developped swallowing difficulties and a decreased vigilance; therefore we assumed that swallowing troubles and decrease of vigilance could be responsible for bronchopulmonary infection. Patients with a low respiratory response to CO2 have higher risk of developping pulmonary complications and can be detected before surgery by this non-invasive test and by the measure of PaCO2.
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