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  • Title: Evaluation of renal concentrating ability with DDAVP and pitressin.
    Author: Herbai G, Ljunghall S.
    Journal: Scand J Urol Nephrol; 1983; 17(1):69-71. PubMed ID: 6867627.
    Abstract:
    This paper reports an attempt to develop a rapid test of the renal concentrating ability using a newly synthetized vasopressin analogue, DDAVP (1-desamino-8-D-arginine-vasopressin), which was given intravenously in a dose of 2 micrograms. Patients investigated for various endocrinological disorders were evaluated with both DDAVP and pitressin. There was a good correlation between the maximal urine osmolalities with both tests. Since DDAVP has fewer side effects and a more rapid onset of action it appears advantageous for investigations of renal concentrating ability.
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