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  • Title: Maternal exposure to exogenous sex hormones in relation to birth weight of offspring.
    Author: Polednak AP, Janerich DT, Glebatis DM.
    Journal: Teratology; 1983 Apr; 27(2):223-9. PubMed ID: 6867944.
    Abstract:
    Birth weight was analyzed among singleton live births (N = 665) in Upstate New York in 1974 to women who used oral contraceptives (OC) in comparison to live births to women who used no contraceptives (N = 716), within 11 months prior to last menstrual period (LMP). In addition, birth weight was examined among live births to women who received hormone support therapy (N = 97) and hormone pregnancy tests (N = 75) during pregnancy. There was no evidence for a reduction in mean birth weight, or an increase in frequency of lower weights, among births to OC users, including those who stopped using OC within 2 months of LMP. Generally similar findings held within three maternal age groups (less than 25, 25-29, and 30-39 years). There was no evidence for a reduction in birth weight among offspring of women who received hormone pregnancy tests. Mean birth weight was relatively low among male and female births to women who received hormone therapy for "threatened abortion," but this may reflect the selection of women for such treatment rather than an effect of exogenous hormones on fetal growth. Birth weight was analyzed among singleton live births (N=665) in upstate New York in 1974 to women who had used no contraceptives (N=716) within 11 months prior to the last menstrual period (LMP). In addition, birth weight was examined among live births to women who received hormone support therapy (N=97) and hormone pregnancy tests (N=75) during pregnancy. There was no evidence for a reduction in mean birth weight, or an increase in frequency of lower weights among births to OC users, including those who stopped using OCs within 2 months of LMP. Generally similar findings held within 3 maternal age groups (25, 25-29, 30-39 years). There was no evidence for a reduction in birth weight among offspring of women who received hormone pregnancy tests. Mean birthweight was relatively low among male and female births to women who did receive hormone therapy for threatened abortion but this may reflect the selection of women for such treatment rather than an effect of exogenous hormones on fetal growth.
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