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  • Title: NK cell activity in pulmonary tuberculosis.
    Author: Yoneda T, Kasai M, Ishibashi J, Nishikawa K, Tokunaga T, Mikami R.
    Journal: Br J Dis Chest; 1983 Apr; 77(2):185-8. PubMed ID: 6871086.
    Abstract:
    Natural killer (NK) cell activity, which may provide defence mechanism in the immune surveillance system, was studied in 38 patients with active pulmonary tuberculosis and 54 sex-, and age-matched healthy controls. The mean NK cell activity in patients with active pulmonary tuberculosis (58.7 +/- 26.4%) was significantly higher (P less than 0.001) than that in healthy controls (17.4 +/- 12.2%). Classifying the patients into three groups according to the state of excretion of tubercle bacilli, the mean NK cell activity in newly diagnosed patients was 43.2 +/- 20.7%, in advanced disease 59.4 +/- 30.3%, and in successfully treated patients 71.9 +/- 25.9%.
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