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  • Title: Biosynthesis of a low molecular weight collagen by rabbit growth plate cartilage organ cultures.
    Author: Remington MC, Bashey RI, Brighton CT, Jimenez SA.
    Journal: Coll Relat Res; 1983 May; 3(3):271-7. PubMed ID: 6872493.
    Abstract:
    Analysis of [14C]-proline labeled proteins synthesized by organ cultures of rabbit growth plate cartilage slices revealed that this tissue synthesized a low molecular weight collagen in addition to Type II, 1 alpha, 2 alpha, and 3 alpha collagens. This collagen appears to be a distinct molecular species on the basis of electrophoretic mobility, hydroxyproline content and cyanogen bromide peptide mapping. In subsequent studies, a non-disulfide-bonded, higher molecular weight form of the same molecule was identified.
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