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  • Title: [Evaluation of clinical data and effort test in patients with angina pectoris: an approach to a multivariate analysis in different groups].
    Author: Miraglia G, Melacini P, Mason FM, Egloff C, Schiavinato ML, Cirillo D, Chioin R, Stritoni P, Dalla Volta S.
    Journal: G Ital Cardiol; 1983; 13(1):23-31. PubMed ID: 6873536.
    Abstract:
    One-hundred and eighty-nine patients who underwent cardiac catheterization for suspected ischemic heart disease were assigned to four different groups depending on the number of diseased vessels (0, 1, 2, 3), the dominant artery and the presence of left main coronary stenosis. Among the 45 parameters obtained from history, physical examination, E.C.G., and exercise test multivariate analysis identified (positive stress test, maximal systolic blood pressure, documented myocardial infarction, maximal heart rate, ipercholesterolemia, lateral myocardial infarction, angina during stress test) that were statistically significant. A score system was devised on the basis of the summed-up value of the seven parameters. When the patients were assigned, according to the score, to one of the previously mentioned 4 groups, the classification proved to be correct in 54% of the cases. When we divided the patients in two groups with or without coronary artery disease so that the attribution turned out to be correct in 92% of the cases (sensitivity 94%, specificity 77%), whereas when based on ST segment depression only, the classification was correct in 85% of the cases (sensitivity 84%, specificity 88%).
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