These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immunotherapy of murine tumor with syngeneic antitumor serum plus BCG.
    Author: Yamazaki M, Saito M, Abe S, Mizuno D.
    Journal: Jpn J Exp Med; 1983 Feb; 53(1):27-32. PubMed ID: 6876475.
    Abstract:
    Murine tumor suppression was observed on combination therapy with antitumor serum and BCG at a low dose. However, no tumor suppression was observed with a relatively high dose of 400 micrograms BCG. Macrophages from mice given a high dose of BCG showed low cytolytic activity but high phagocytic activity in vitro. In BCG- sensitized mice, BCG was effective on early ascitic tumors. Moreover, combination therapy with antitumor serum and BCG was effective on tumors at an advanced stage. These results suggest that in combination, antiserum and BCG have synergistic therapeutic effects on tumors of BCG-sensitized and nonsensitized hosts.
    [Abstract] [Full Text] [Related] [New Search]