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  • Title: Attenuation of Eimeria mivati (= mitis) by selection for precocious development.
    Author: McDonald V, Ballingall S.
    Journal: Parasitology; 1983 Jun; 86 (Pt 3)():371-9. PubMed ID: 6877864.
    Abstract:
    By selection for early development of oocysts during serial passage through chickens the pre-patent period of the Houghton (H) strain of Eimeria mivati (= mitis) was reduced by over 20 h. The precocious parasite is less pathogenic than the H strain and has a reduced reproductive potential. Chicks inoculated with the precocious parasite were protected against challenge with the H strain. The pathogenicity, immunogenicity and reproduction of precocious E. mivati and an attenuated egg-adapted line of E. mivati were compared. Although the precocious parasite produced more oocysts than the egg-adapted parasite in chickens, neither parasite induced loss of weight and both were immunogenic.
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