These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Treatment of fracturing renal osteodystrophy by desferrioxamine.
    Author: Ackrill P, Day JP, Garstang FM, Hodge KC, Metcalfe PJ, Benzo Z, Hill K, Ralston AJ, Ball J, Denton J.
    Journal: Proc Eur Dial Transplant Assoc; 1983; 19():203-7. PubMed ID: 6878234.
    Abstract:
    Aluminium removal by desferrioxamine chelation has been demonstrated in three long-term haemodialysis patients with dialysis encephalopathy and fracturing renal osteodystrophy. Aluminium concentrations in serum and in both bone marrow and bone trabeculae, determined separately in transiliac biopsy specimens, fell significantly over the treatment period. Bone aluminium removal was confirmed by specific histochemical staining. In two patients osteomalacia disappeared, and in two patients osteitis fibrosa emerged but improved in one following vitamin D therapy. We conclude that desferrioxamine is capable of mobilising aluminium from bone and that the calcification defect in fracturing renal osteodystrophy may be overcome.
    [Abstract] [Full Text] [Related] [New Search]