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  • Title: Exocrine pancreatic hypersecretion in Brazilian alcoholics.
    Author: Neves MM, Borges DR, Vilela MP.
    Journal: Am J Gastroenterol; 1983 Aug; 78(8):513-6. PubMed ID: 6881118.
    Abstract:
    Thirty percent of alcoholic patients without clinical evidence of pancreatic or hepatic disease showed hypersecretion of pancreatic bicarbonate in all three test periods after stimulation with secretin and secretin-cholecystokinin, and an increased amount of protein in the duodenal aspirate of the first test period, probably due to ductal wash-out. This hypersecretion must be taken into account when the secretion or secretin-cholecystokinin tests of alcoholics are interpreted, and, indeed, may be useful in identifying possible early pancreatic dysfunction that precedes insufficiency and clinical symptoms.
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