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  • Title: [Infantile myoclonic encephalopathy with opsoclonus and neuroblastoma. Apropos of 2 cases].
    Author: Palacio M, Ruiz-Benito MA, Mondragón F, Solórzano C, Tovar JA.
    Journal: An Esp Pediatr; 1983 Feb; 18(2):118-22. PubMed ID: 6881734.
    Abstract:
    Two cases of infantile myoclonic encephalopathy with opsoclonus and neuroblastoma are reported. One of them was observed in a 16-month-old boy and the remaining one in a 13-month-old girl. In both cases the tumour was a stade III abdominal neuroblastoma. Urinary catecolamine excretion was increased in the girl and that of VMA in both patients. Treatment of the tumour with surgery, radiotherapy and chemotherapy resulted in a immediate disappearance of the neurologic picture in the girl. The same measures were equally successful in the boy implemented with a course of ACTH. Both children are free of tumour three years later, and they do not bear any psychomotor sequelae. The main features of this rare association are briefly commented.
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