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  • Title: High pressure liquid chromatographic determination of oxazepam dosage forms: collaborative study.
    Author: Bargo ES.
    Journal: J Assoc Off Anal Chem; 1983 Jul; 66(4):864-6. PubMed ID: 6885692.
    Abstract:
    A reverse phase high pressure liquid chromatographic method for the determination of oxazepam in tablets and capsules was collaboratively studied by 9 laboratories. Collaborators were supplied with 6 samples that included synthetic and commercial formulations. Tablet and capsule composites are diluted with methanol and filtered. Oxazepam is determined at 254 nm by using a C18 column. Mean recoveries of oxazepam from synthetic tablet and capsule formulations were 97.2 and 99.0%, respectively. Mean coefficients of variation for tablets and capsules ranged from 1.85 to 2.86%. The method has been adopted official first action.
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