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  • Title: [Chromatid exchanges as parameters of the chronon].
    Author: Gedda L, Brenci G, Ziparo R.
    Journal: Boll Soc Ital Biol Sper; 1982 Jul 30; 58(14):895-9. PubMed ID: 6889882.
    Abstract:
    In chronogenetic theory different genes have a different stability ("ergon") which determines the duration ("chronon") of their action. The ergon/chronon of each gene is considered to be inherited. In order to verify whether genomic stability is a heritable trait, the frequency of sister chromatid exchanges (SCE) was observed in a sample of 12 MZ twin pairs distributed as follows: (formula; see text) The minimum intrapair variability as against the high interpair variability as to mean S.C.E. counts supports the hypothesis of genetic control on S.C.E. frequency. The increase in S.C.E. frequency in older pairs indicates the age-dependence of the phenomenon. The study will be extended to both DZ pairs and older twin pairs.
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