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  • Title: [Pathophysiology and therapy of magnesium deficiency in pregnancy].
    Author: Bartl W, Riss P.
    Journal: Z Geburtshilfe Perinatol; 1982; 186(6):335-7. PubMed ID: 6891868.
    Abstract:
    We determined serum magnesium(Mg)-levels in 67 pregnant women in late pregnancy. 42 gravidae complained of nightly muscle cramps; 21 of them received 1.8 g monomagnesiumaspartate twice daily per mouth for 4 weeks. 2 and 4 weeks after the initiation of therapy serum Mg-levels were again determined. Serum Mg-levels were lower in pregnant women as compared to a control group of non pregnant women. Gravidae complaining of muscle cramps had significantly lower serum Mg-levels than women without muscle cramps. The administration of Mg was associated with a significant rise in serum Mg-levels as early as 2 weeks after the initiation of therapy. Our study indicates that nightly muscle cramps during pregnancy might be a sign of a latent magnesium deficiency which can be influenced by oral magnesium.
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