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  • Title: Butriptyline: improved gas-liquid chromatographic method using a nitrogen-phosphorus detector for its determination in serum.
    Author: Gonzalez R, Kraml M.
    Journal: Clin Biochem; 1980 Aug; 13(4):141-3. PubMed ID: 6893814.
    Abstract:
    We report a sensitive and specific method for the determination of butriptyline concentrations in serum by gas-liquid chromatography with a nitrogen phosphorus detector. The detection limit is 2 ng/ml, based on 3 ml of serum or plasma. The method has been validated in human volunteers receiving a single oral dose of 75 mg butriptyline hydrochloride.
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