These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Synthesis of rubomycin 13-tert-butoxycarbonylhydrazone and the study of its antitumor action].
    Author: Povarov LS, Gol'dberg LE, Bazhanov VS, Olsuf'eva EN, Averbukh LA.
    Journal: Antibiotiki; 1981 Nov; 26(11):813-6. PubMed ID: 6895688.
    Abstract:
    13-Tert-butoxycarbonylhydrazone of rubomycin was prepared on interaction of rubomycin with tert-butoxycarbonylhydrazine. The new compound showed a high antitumor activity with respect to lymphosarcoma LIO-1 and Garding-Passey melanoma. The compound had no advantages over the initial rubomycin in the treatment of these tumors, was inferior to rubomycin with respect to its activity against leukemia P-388 and unlike rubomycin had practically no effect on leukemia L-1210.
    [Abstract] [Full Text] [Related] [New Search]