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  • Title: Bile acids. OV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid.
    Author: Shaw R, Elliott WH.
    Journal: J Lipid Res; 1978 Aug; 19(6):783-7. PubMed ID: 690519.
    Abstract:
    Artifacts formed by methylation of chenodeoxycholic acid with diazomethane are identical to the synthetic 3alpha- and 7 alpha-monomethyl ethers of methyl chenodeoxycholate. The extent of formation of these artifacts with time has been studied. No detectable artifacts were found with 2,2-dimethoxypropane as the methylating agent.
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