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  • Title: [Effects of subacute treatment with clomiphene, ethamoxytriphetol (Mer-25), and nafoxidine on blood calcium and bone density in rats].
    Author: Sala Blanco J, Casas Tineo B, Hidalgo A.
    Journal: Rev Esp Oncol; 1982; 29(3):497-503. PubMed ID: 6927021.
    Abstract:
    The authors study the effect of clomiphene, ethamoxytriphetol and nafoxidine on calcemia and bone density of the rat. These antiestrogens induce hypercalcemia, reproducing the bone radiologic changes produced after castration. The different effects obtained in normal and ovariectomized rats are probably due to the small estrogenic activity of antiestrogens.
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