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  • Title: [Circulating immune complexes in the serum of tumor patients].
    Author: Alvarez R, García Gómez A, Subiza JL, Domínguez J, Bootello A, Coll J.
    Journal: Rev Esp Oncol; 1982; 29(4):727-34. PubMed ID: 6927370.
    Abstract:
    The conditions for the detection of circulating immune complexes (CIC) were established by combination of polyethylene glycol precipitation with a nephelometric determination on the precipitate of endogenous C1q. The CIC precipitated from the sera of patients with breast carcinoma, malignant melanoma or autoimmune diseases were dissociated in SDS-beta-mercaptoethanol buffer and no differences were observed in the electrophoretic patterns os polyacrylamide gels allowing to characterize tumour specific antigens.
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