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  • Title: [Urological complications in patients with multiple sclerosis (author's transl)].
    Author: Kiesswetter H, Flamm J, Hennrich F, Summer K, Schober W.
    Journal: Wien Klin Wochenschr; 1980 Jan 04; 92(1):16-22. PubMed ID: 6929626.
    Abstract:
    63 patients with multiple sclerosis underwent urodynamic evaluation. Hyperreflexia of the bladder was found in 64% and areflexia in 8%. Hypertrophy or sclerosis of the bladder neck (internal sphincter) was detected in 27% of the patients and a spastic external sphincter (dyssynergia) was encountered in 57%. 16 patients were admitted for surgery: 9 for TUR of the bladder neck, 5 for percutaneous selective sacral nerve block, 2 for ileal diversion, 2 for prolonged bladder distension and 1 for nephrectomy for staghorn calculi of the renal pelvis. Highly effective conservative therapy is available in the form of Lioresal for treatment of the hyperactive detrusor muscle and Dibenzyran - an alpha-adrenergic blocking agent - to relieve bladder neck spasticity.
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